Pharmaceutical Product Guide » ADX10059 http://www.pharmaceuticalproductguide.com/blog A comprehensive guide to pharmaceutical products for medical professionals Fri, 11 Jun 2010 09:15:33 +0000 http://wordpress.org/?v=2.8.2 en hourly 1 Development Of ADX10059 Ended For Long-Term Use http://www.pharmaceuticalproductguide.com/blog/2010/01/22/development-of-adx10059-ended-for-long-term-use/ http://www.pharmaceuticalproductguide.com/blog/2010/01/22/development-of-adx10059-ended-for-long-term-use/#comments Fri, 22 Jan 2010 05:22:05 +0000 Kimberly O'Brien http://www.pharmaceuticalproductguide.com/blog/?p=196 Addex PharmaceuticalsAddex Pharmaceuticals announced that based on preliminary review of the unblinded data from study 206, it has terminated development of ADX10059 for chronic indications, including long term treatment of gastroesophageal reflux disease and migraine prophylaxis. In study 206 the incidence of alanine transaminase (ALT) levels greater than five times the upper limit of normal ( > 5xULN) levels was 6% (16 of 257 patients); however, bilirubin remained normal in all but one patient.

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